Facile one-pot synthesis of 5-substituted hydantoins.
نویسندگان
چکیده
5-Substituted and 5,5-disubstituted hydantoins are synthesised from the corresponding aldehydes or ketones, using a one-pot, gallium(III) triflate-catalysed procedure that is compatible with a range of substrates and solvents.
منابع مشابه
Regioselective multicomponent sequential synthesis of hydantoins.
The development of new practical and green methods for the synthesis of small heterocycles is an attractive area of research due to the well-known potential of heterocyclic small molecule scaffolds in the drug discovery process. Herein we report a one-pot, three-component sequential procedure for the synthesis of diversely 1,3,5- and 1,3,5,5-substituted hydantoins, in high yields and very mild ...
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 6 6 شماره
صفحات -
تاریخ انتشار 2008